Optisol vs Dexsol as storage media for preservation of human corneal epithelium

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A randomized, double-masked clinical trial of Optisol-GS vs Chen Medium for human corneal storage.

OBJECTIVE To determine whether the clinical outcome of corneal transplantation performed with tissue stored in Chen Medium (CM; Chen Laboratories, Phoenix, Md) is superior to that of Optisol-GS (Chiron Ophthalmics, Irvine, Calif). DESIGN Randomized, double-masked trial. PARTICIPANTS AND SETTING Ninety patients undergoing corneal transplantation at a tertiary center. INTERVENTION Donor cor...

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Evaluation of the long-shelf life honey milk As a storage media for preservation of avulsed teeth

Introduction: Tooth avulsion is defined as the complete displacement of the tooth from its alveolar socket which causes damage to the periodontal ligament structure, cementum, alveolar bone, gingiva, and dental pulp. The purpose of this study was to determine the ability of long-shelf life honey milk to serve as a temporary storage medium for the maintenance of periodontal ligament (PDL) cell v...

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Effects of organ culture and Optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium.

PURPOSE A previous report has described the use of eye bank storage of cultured human limbal epithelial cells (HLECs) to provide a reliable source of tissue for treating limbal stem cell deficiency. In the present study, conventional organ culture (OC) storage and Optisol-GS (Bausch & Lomb, Irvine, CA) storage of cultured HLECs were compared. METHODS Three-week HLEC cultures were either organ...

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Glutathione Preservation during Storage of Rat Lenses in Optisol-GS and Castor Oil

BACKGROUND Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The aim of the study was to examine the effects of Optisol-GS and castor oil on lens cond...

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Effect of death-to-preservation time on donor corneal epithelium.

PURPOSE Surface disease is one of multiple variables affecting the quality of the postkeratoplasty donor cornea. Trauma to Bowman's layer before and during harvesting can denude the donor epithelium and result in epithelial defects in the donor following penetrating keratoplasty. Eye banks use death-to-preservation (DP) time intervals as long as 18 hours. This study evaluates the effects of hig...

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ژورنال

عنوان ژورنال: Eye

سال: 2004

ISSN: 0950-222X,1476-5454

DOI: 10.1038/sj.eye.6700693